La necesaria modernización del régimen presupuestario de la administración y su control

La disciplina presupuestaria clásica se ha venido caracterizando por una atención casi exclusiva al procedimiento de gasto, y en particular a las clasificaciones económicas y orgánicas, con niveles muy desagregados de vinculación y rigurosos controles simultáneos, atendiendo casi exclusivamente a la legalidad y regularidad del proceso de gasto. Al mismo tiempo han proliferado entes instrumentales de la más diversa naturaleza cuyo objeto, en muchos casos, no es otro que romper esas rigidices de la disciplina presupuestaria tradicional en aras de una mayor flexibilidad en la gestión. Más recientemente se han creado nuevas fórmulas que tratan de incorporar una mayor atención a los resultados y al logro de objetivos. En este nuevo contexto se incorporan propuestas tendentes a la configuración de una nueva disciplina presupuestaria para la Administracion General que permita incorporar progresivamente algunas de las soluciones más flexibles propugnadas por la nueva gestión pública evitando la creación de entes instrumentales por exclusivas razones presupuestarias

A Study on the Parametric Design Parameters That Influence Environmental Ergonomics and Sustainability

The publication is part of Grant FJC2021-047711-I, funded by MCIN/AEI/10.13039/5011000 11033 and by the European Union NextGenerationEU/PRTR awarded to Carmen Díaz-López through contract reference USE-23442-MThe parametric design applied to the built environment is critical to creating sustainable and resilient spaces. However, this research field involves a vast and complex amount of disconnected information. Therefore, this paper aims to analyse research trends in applying parametric design to optimise sustainability and environmental ergonomics parameters in built environments. The following specific objectives are identified to meet this objective: (i) a quantitative analysis based on a systematic literature review; (ii) a qualitative review based on a performance analysis and scientific mapping; and (iii) a comparative analysis of case studies applying parametric language for the optimisation of sustainability and environmental ergonomics parameters. The 1045 research records covering 1974 to 2021 illustrate a field in development that evolves from early digital advances to climate change adaptations, the circular economy and resilience. It highlights the importance of applying bioclimatic techniques in the built environment, identifying the most optimised measures and encouraging the creation of guidelines to serve as a protocol for future studies, contributing to the existing body of knowledge by highlighting trends, establishing research themes, outlining research networks and suggesting areas for further studies.MCIN/AEI FJC2021-047711-IEuropean Commission USE-23442-

Dimensions of Charity versus Development: The Century-Old Debate in the Profession of Social Work

The social work profession seeks different objectives and utilizes different methodologies and interventions in the countries in which it operates around the world. Furthermore, it operates within drastically different political, economic and cultural contexts. For these reasons, it is difficult to identify an ideal universal method of intervention.For approximately a century, social work practitioners and academicians have debated whether the profession should focus its efforts on providing charity and relief services or promoting socio-economic development and self-sufficiency. This article defines the concepts of charity and socioeconomic development and analyzes the main dimensions of this debate in an effort to deepen our understanding of how to best promote the wellbeing of individuals and communities

Seguimiento de estudiantes y egresados en los Dobles Grados de Matemáticas

El proyecto tiene carácter interfacultativo e incluye a las facultades de CC. Económicas y Empresariales, Ciencias Físicas, Informática y Ciencias Matemáticas. Es una continuación natural del PIMCD-287 “Elaboración de estudios para el seguimiento del rendimiento académico de los estudiantes de los dobles grados en Matemáticas”. El objetivo global del proyecto ha consistido en el de avanzar en el trabajo iniciado con el proyecto anterior concedido en el curso 2014-15 y profundizar en el análisis de las distintas acciones que se han llevado a cabo a través de las encuestas realizadas al alumnado, reuniones y el debate sobre aprendizaje/evaluación continua en Grados y dobles Grados. Se continuó con la revisión del modelo de coordinación horizontal académico-docente, con el fin de dotarlo de una mayor eficacia

Preliminary results of a catastrophic model of extreme wind gust situations in peninsular Spain

Póster presentado en: 10th EUMETNET Data Management Workshop celebrado en St. Gallen, Suiza, del 28 al 30 de octubre de 2015.The CCS (Spanish Insurance Compensation Consortium) is the Spanish Agency that provides insurance coverage against weather events that involve an extraordinary risk. One of the extraordinary risks covered by the CCS refers to extraordinary wind, defined as those with wind gusts exceeding 120 km/h. The accurate delimitation of the areas in which this condition is met shows considerable difficulties in our country because of the lack of wind observations and the complexity of the terrain. The operational procedure performed at AEMET (Spanish Meteorological Agency) for estimating the areas with maximum wind gusts applies a geostatistical technique, the universal kriging, based on the observational data of maximum wind gust and drawing also on external variables: terrain elevation, distance from the shore, and the HIRLAM (High Resolution Limited Area Model) forecasting model output of maximum wind gust field. Extreme meteorological events sometimes go unnoticed but frequently become apparent due their impact on society with its corresponding consequences. Moreover, the catastrophic nature of a phenomenon depends not only on the extreme value that the climate element takes on, but also on other factors, such as population distribution or geomorphological features, among many others. In this work we present some preliminary steps in the development of a catastrophic model of extreme wind gust situations in peninsular Spain. The main aim of this model is to provide significant information for covering risk against future extreme wind situations, as well as assessing the liability owing to this risk on a year time-frame. The first steps in the development of this model are: a) the generation of climatology of the areas under extraordinary wind going back to 2010 and, b) the estimation of incurred covered loss in these years based on data from the insurer. The following step will be the estimation of a local (at municipality level at best) expected loss function from extraordinary winds depending on the intensity of the event.This project is being sponsored by CCS

Development of a homogeneous long monthly precipitation dataset for Spain

Póster presentado en: 10th EMS Annual Meeting - 8th European Conference on Applied Climatology (ECAC) celebrado en Zurich, los días 13-17 de septiembre de 2010The purpose of this study is to extend, revise, improve and update the Spanish monthly/annual centenarian precipitation series in order to achieve more consistent variability and trend analyses. We present the compilation of a dataset integrated by 66 long monthly precipitation series, which covers mainland Spain and the Balearic Island

A monthly precipitation database for Spain (1851–2008): reconstruction, homogeneity and trends

The compilation and reconstruction of a dataset integrated by 66 long monthly precipitation series, covering mainland Spain and the Balearic Islands, is presented. The reconstruction is based on the hypothesis that the cessation of data recording at one observatory is followed by the establishment of a new observatory very close to the closed one. In order to detect and adjust for possible multiple change points or shifts that could exist in the precipitation series, the R-package CLIMATOL V2.0 is used. This method enables to take advantage of the whole historical Spanish precipitation network in the detection and correction of inhomogeneities. The analysis of annual precipitation trends indicate a high temporal variability. Negative trends dominate for the period 1951–2008 but not for all observatories. On the other hand, positive trends can be detected in the northern Spain for 1902–2008

Role of microRNA in epithelial to mesenchymal transition and metastasis and clinical perspectives

The microRNAs (miRNAs) are a class of small, 20–22 nucleotides in length, endogenously expressed noncoding RNAs that regulate multiple targets posttranscriptionally. Interestingly, miRNAs have emerged as regulators of most physiological and pathological processes, including metastatic tumor progression, in part by controlling a reversible process called epithelial-to-mesenchymal transition (EMT). The activation of EMT increases the migratory and invasive properties fundamental for tumor cell spread while activation of the reverse mesenchymal-to-epithelial transition is required for metastasis outgrowth. The EMT triggering leads to the activation of a core of transcription factors (EMT-TFs) – SNAIL1/SNAIL2, bHLH (E47, E2-2, and TWIST1/TWIST2), and ZEB1/ZEB2 – that act as E-cadherin repressors and, ultimately, coordinate EMT. Recent evidence indicates that several miRNAs regulate the expression of EMT-TFs or EMT-activating signaling pathways. Interestingly, some miRNAs and EMT-TFs form tightly interconnected negative feedback loops that control epithelial cell plasticity, providing self-reinforcing signals and robustness to maintain the epithelial or mesenchymal cell status. Among the most significant feedback loops, we focus on the ZEB/miR-200 and the SNAIL1/miR-34 networks that hold a clear impact in the regulation of the epithelial-mesenchymal state. Recent insights into the p53 modulation of the EMT-TF/miRNA loops and epigenetic regulatory mechanisms in the context of metastasis dissemination will also be discussed. Understanding the regulation of EMT by miRNAs opens new avenues for the diagnosis and prognosis of tumors and identifies potential therapeutic targets that might help to negatively impact on metastasis dissemination and increasing patient survivalAC is funded by grants of the Spanish Ministry of Economy and Competitiveness, formerly Innovation and Sciences, (SAF2010-21143; Consolider-Ingenio CSD2007-00017) and Association for International Cancer Research (grant 12-1057). GMB is funded by SAF2010-20175, AECC-2011 and Instituto de Salud Carlos III (ISCIII) PI13/00132. GMB and AC are funded by the Community of Madrid (S2010/BMD-2303) and the Instituto de Salud Carlos III (RETIC-RD12/0036/0007). ADL is a postdoctoral researcher funded by the Sara Borrell program (ISCIII)

Current contents : análisis de una experiencia

In the present economic conditions of the acquisition of important scientific journals becomes difficult, the possibility of compensating such situation with the obtaining of reprints through the Current Contents is presented

Lactic Acid Bacteria and Yeast Inocula Modulate the Volatile Profile of Spanish-Style Green Table Olive Fermentations

In this work, Manzanilla Spanish-style green table olive fermentations were inoculated with Lactobacillus pentosus LPG1, Lactobacillus pentosus Lp13, Lactobacillus plantarum Lpl15, the yeast Wickerhanomyces anomalus Y12 and a mixed culture of all them. After fermentation (65 days), their volatile profiles in brines were determined by gas chromatography-mass spectrometry analysis. A total of 131 volatile compounds were found, but only 71 showed statistical differences between at least, two fermentation processes. The major chemical groups were alcohols (32), ketones (14), aldehydes (nine), and volatile phenols (nine). Results showed that inoculation with Lactobacillus strains, especially L. pentosus Lp13, reduced the formation of volatile compounds. On the contrary, inoculation with W. anomalus Y12 increased their concentrations with respect to the spontaneous process, mainly of 1-butanol, 2-phenylethyl acetate, ethanol, and 2-methyl-1-butanol. Furthermore, biplot and biclustering analyses segregated fermentations inoculated with Lp13 and Y12 from the rest of the processes. The use of sequential lactic acid bacteria and yeasts inocula, or their mixture, in Spanish-style green table olive fermentation could be advisable practice for producing differentiated and high-quality products with improved aromatic profile.Gobierno de España-OliFilm-AGL-2013-48300-